Drug: Acova (argatroban)

What is argatroban (Acova)? Argatroban keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur while receiving heparinArgatroban is used to treat or prevent blood clots in people who have thrombocytopenia (low levels of platelets in the blood) caused by using heparin. Argatroban is sometimes used in people who are undergoing a procedure called angioplasty (to open blocked arteries).Argatroban may also be used for purposes not listed in this medication guide.

Source: http://www.emedicinehealth.com

What are the possible side effects of argatroban (Acova)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have a serious side effect such as:
  • feeling like you might pass out;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • blood in your urine;
  • black, bloody, or tarry stools;
  • coughing up blood or vomit that looks like coffee grounds;
  • any bleeding that will not stop;
  • pain or burning when you urinate;
  • sudden numbness or weakness, problems with vision, speech, or balance;
  • sudden severe headache, confusion, sudden changes in your senses of taste or touch;
  • fever, chills, body aches, flu symptoms;
  • cough with yellow or green mucus, stabbing chest pain, feeling short of breath;
  • slow heart rate, weak pulse, slow breathing (breathing may stop); or
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.
Less serious side effects may include:
  • nausea, vomiting, diarrhea, stomach pain;
  • headache;
  • back pain; or
  • bleeding around the IV needle.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect argatroban (Acova)? Tell your doctor about all other medications you use or have recently received to prevent blood clots, such as:
  • a blood thinner such as heparin or warfarin (Coumadin, Jantoven);
  • abciximab (ReoPro), anagrelide (Agrylin), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox), eptifibatide (Integrelin), prasugrel (Effient), ticlopidine (Ticlid), tirofiban (Aggrastat);
  • dabigatran (Pradaxa), bivalirudin (Angiomax), lepirudin (Refludan);
  • dalteparin (Fragmin), enoxaparin (Lovenox), fondaparinux (Arixtra), tinzaparin (Innohep); or
  • alteplase (Activase), tenecteplase (TNKase), urokinase (Abbokinase).
This list is not complete and other drugs may interact with argatroban. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Source: http://www.emedicinehealth.com

What happens if I overdose (Acova)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

Source: http://www.emedicinehealth.com

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