What other drugs will affect rectal aspirin (Aspirin)?
Ask your doctor before using an antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking any of these medicines while you are using aspirin may cause you to bruise or bleed easily.Ask a doctor or pharmacist if it is safe for you to use rectal aspirin if you are also using any of the following drugs:
- alprostadil (Caverject, Edex);
- eptifibatide (Integrilin);
- tirofiban (Aggrastat);
- probenecid (Benemid);
- divalproex (Depakote) or valproic acid (Depacon, Depakene);
- an antacid or laxative;
- a blood thinner such as heparin or warfarin (Coumadin, Jantoven);
- cancer medicine such as abciximab (Reopro), methotrexate (Folex, Rheumatrex, Trexall);
- insulin or oral diabetes medicine;
- an antibiotic such as cefemandole (Maxipime), cefotetan (Cefotan), ciprofloxacin (Cipro), demeclocycline (Declomycin), doxycycline (Doryx, Periostat, Vibramycin), minocycline (Dynacin, Minocin), norfloxacin (Noroxin), ofloxacin (Floxin), piperacillin (Pipracil), tetracycline (Ala-Tet, Sumycin, Tetracap), ticarcillin (Ticar), vancomycin (Vancocin);
- an antifungal such as itraconazole (Sporanox) or ketoconazole (Nizoral);
- medication used to prevent blood clots, such as alteplase (Activase), clopidogrel (Plavix), dipyridamole (Persantine), ticlopidine (Ticlid), and urokinase (Abbokinase);
- salicylates such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal; or
- NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.
This list is not complete and other drugs may interact with rectal aspirin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.