Drug: Aspirin (aspirin (rectal))

What is rectal aspirin (Aspirin)? Aspirin is in a group of drugs called salicylates. It works by reducing substances in the body that cause pain and inflammation. Aspirin also reduces fever.Rectal aspirin is given as a suppository to reduce pain, inflammation, and fever. Aspirin is also used to treat the symptoms of arthritis and rheumatic fever.Rectal aspirin may also be used for purposes not listed in this medication guide.

Source: http://www.emedicinehealth.com

What are the possible side effects of rectal aspirin (Aspirin)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Stop using this medicine and call your doctor at once if you have a serious side effect such as:
  • black, bloody, or tarry stools;
  • blood in your urine;
  • coughing up blood or vomit that looks like coffee grounds;
  • pale skin, easy bruising or bleeding;
  • wheezing, chest tightness, trouble breathing;
  • decreased hearing or ringing in the ears;
  • seizure (convulsions); or
  • dizziness, confusion, or hallucinations.
Less serious side effects may include:
  • nausea, vomiting, stomach pain; or
  • rectal irritation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect rectal aspirin (Aspirin)? Ask your doctor before using an antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). Taking any of these medicines while you are using aspirin may cause you to bruise or bleed easily.Ask a doctor or pharmacist if it is safe for you to use rectal aspirin if you are also using any of the following drugs:
  • alprostadil (Caverject, Edex);
  • eptifibatide (Integrilin);
  • tirofiban (Aggrastat);
  • probenecid (Benemid);
  • divalproex (Depakote) or valproic acid (Depacon, Depakene);
  • an antacid or laxative;
  • a blood thinner such as heparin or warfarin (Coumadin, Jantoven);
  • cancer medicine such as abciximab (Reopro), methotrexate (Folex, Rheumatrex, Trexall);
  • insulin or oral diabetes medicine;
  • an antibiotic such as cefemandole (Maxipime), cefotetan (Cefotan), ciprofloxacin (Cipro), demeclocycline (Declomycin), doxycycline (Doryx, Periostat, Vibramycin), minocycline (Dynacin, Minocin), norfloxacin (Noroxin), ofloxacin (Floxin), piperacillin (Pipracil), tetracycline (Ala-Tet, Sumycin, Tetracap), ticarcillin (Ticar), vancomycin (Vancocin);
  • an antifungal such as itraconazole (Sporanox) or ketoconazole (Nizoral);
  • medication used to prevent blood clots, such as alteplase (Activase), clopidogrel (Plavix), dipyridamole (Persantine), ticlopidine (Ticlid), and urokinase (Abbokinase);
  • salicylates such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal; or
  • NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.
This list is not complete and other drugs may interact with rectal aspirin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Source: http://www.emedicinehealth.com

What happens if I overdose (Aspirin)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include severe nausea, vomiting, or diarrhea, ringing in the ears, confusion, headache, increased thirst, severe drowsiness, uncontrolled muscle twitching, shortness of breath, bloody urine, hallucinations, or seizure (convulsions).

Source: http://www.emedicinehealth.com

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