Drug: dexamethasone injection

Glucocorticoids are associated with a variety of side effects based on dose and duration of therapy. Dexamethasone may commonly cause an increase in blood sugar, appetite, insomnia, acne, and nervousness or emotional instability (depression or euphoria). It may also cause impaired wound healing, high blood pressure, raised pressure in the eye, and cataracts. Serious side effects include risk of cardiomyopathy, induced diabetes mellitus, pancreatitis, osteoporosis (bone loss), and conjunctival hemorrhage. REFERENCE: Dexamethasone FDA Prescribing Information.

Source: http://www.medicinenet.com

Yes

Source: http://www.medicinenet.com

Injection solution: 4 mg/mL and 10 mg/ml; 1 mg/ml

Source: http://www.medicinenet.com

Dexamethasone should be stored as intact vials at room temperature, between 20 C to 25 C (68 F to 77 F). Protect from light and heat. Do not freeze. If diluted, use within 24 hours.

Source: http://www.medicinenet.com

The dose for dexamethasone is based on whether is administered intravenously or by intramuscular injection as well as the severity of the condition requiring treatment. Consult the official prescribing information for dosing regimens.

Source: http://www.medicinenet.com

Category C; animal reproduction studies show adverse events with corticosteroid use. Dexamethasone has the potential to cross the placenta to affect fetal growth. Lowest effective doses should be used for the shortest duration of time, with avoidance of dosing in the first trimester to help avoid oral clefts. Low adrenal function may also develop in newborns if corticosteroid exposure occurs while in the womb.

Source: http://www.medicinenet.com

Corticosteroids are excreted in breast milk, and, therefore should be used cautiously by nursing mothers. If dexamethasone is absolutely needed and breastfeeding cannot be stopped, a separation of 4 hours between therapy and breastfeeding is recommended to decrease exposure of the infant to the corticosteroid.

Source: http://www.medicinenet.com

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