Drug: spironolactone

Side effects of spironolactone include:
  • headache,
  • diarrhea,
  • cramps,
  • drowsiness,
  • rash,
  • nausea,
  • vomiting,
  • impotence,
  • irregular menstrual periods, and
  • irregular hair growth.
Fluid and electrolytes imbalance (for example, low sodium, low magnesium, and high potassium) may occur, so patients should be monitored carefully. Enlargement of the male breasts (gynecomastia) may also occur and is related to dose and duration of therapy. It usually reverses upon discontinuation of spironolactone.

Source: http://www.medicinenet.com

Yes

Source: http://www.medicinenet.com

Tablets: 25, 50, and 100 mg

Source: http://www.medicinenet.com

Spironolactone should be stored at room temperature, below 25 C (77 F).

Source: http://www.medicinenet.com

Spironolactone may be taken with or without food. The dosage range is 25-400 mg daily in single or divided doses.
  • The initial dose for treating edema in adults is 100 mg daily as a single dose or divided doses. The dose may be adjusted after 5 days based on response. The recommended dose range is 25 to 200 mg daily. The initial dose should be continued for at least 5 days before increasing the dose. If there is no adequate response after 5 days, a second diuretic may be added.
  • The dose for treating high blood pressure (hypertension) is 50 to 100 mg daily in single or divided doses.
  • The dose for treating hypokalemia is 25 to 100 mg daily.

Source: http://www.medicinenet.com

An active metabolite of spironolactone is secreted in breast milk. To avoid adverse effects in the newborn, mothers should avoid breastfeeding while taking spironolactone. Medically reviewed by Omudhome Ogbru, PharmD Reference: FDA Prescribing Information

Source: http://www.medicinenet.com

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