Drug: METHYLDOPA/HYDROCHLOROTHIAZIDE - ORAL (METH-il-DOE-pa/HYE-droe-KLOR-oh-THYE-a-zide)

This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications: methyldopa and hydrochlorothiazide. Methyldopa works by relaxing blood vessels so blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic). It increases the amount of urine you make, especially when you first start the medication. It also helps to relax the blood vessels so that blood can flow more easily.These medications are used together when 1 drug alone is not controlling your blood pressure. Your doctor may direct you to start taking the individual medications first, and then switch you over to this combination product if this is the best dose combination for you.

Source: http://www.medicinenet.com

Dizziness, lightheadedness, drowsiness, headache, stuffy nose, and weakness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.This medication may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: extreme thirst, very dry mouth, muscle cramps, weakness, fast/irregular heartbeat, confusion.Tell your doctor right away if you have any serious side effects, including: fainting, toe/joint pain, change in the amount of urine (not including the normal increase in urine when you first start this drug), swelling ankles/feet, unexplained/sudden weight gain, muscle spasms/uncontrolled muscle movements, missed/stopped periods, decreased sexual desire/ability, increased breast size (in men), mental/mood changes (such as depression), decrease in vision, eye pain.Methyldopa has rarely caused very serious (rarely fatal) liver disease or low red blood cell count (anemia). Tell your doctor right away if you develop any symptoms of liver disease or anemia, including: unusual tiredness, unexplained fever, dark urine, persistent nausea/vomiting/loss of appetite, severe stomach/abdominal pain, yellowing skin/eyes.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Source: http://www.medicinenet.com

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Information last revised December 2013. Copyright(c) 2013 First Databank, Inc.

Source: http://www.medicinenet.com

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: cisapride, dofetilide, iron products (such as ferrous sulfate, ferrous gluconate), lithium.Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).Check the labels on all your medicines (such as allergy or cough-and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that cause drowsiness or increase your blood pressure. Ask your pharmacist for more details.This medication may interfere with certain laboratory tests (including parathyroid test, protein-bound iodide test, urine catecholamine test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Source: http://www.medicinenet.com

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