Drug: alpha-1 proteinase inhibitor

The most common side effects of alpha-1 proteinase inhibitor are:
  • chills,
  • malaise,
  • headache,
  • rash,
  • hot flush, and
  • pruritus.
  • increase in enzymes used to monitor liver function,
  • shortness of breath,
  • serious hypersensitivity-type reactions or anaphylaxis, and
  • rapid heartbeat.

Source: http://www.medicinenet.com

Yes

Source: http://www.medicinenet.com

Alpha-1 proteinase inhibitor is available in a kit containing a single-use vial of 1000 mg alpha-1 proteinase inhibitor as a lyophilized powder, one 20 ml vial of sterile water for dilution, a transfer needle, and a filter needle.

Source: http://www.medicinenet.com

Alpha-1 proteinase inhibitor should be stored below 25 C (77 F). This medicine does not require refrigeration and should not be stored in the freezer. After mixing, the solution can be kept at room temperature for administration within 3 hours.

Source: http://www.medicinenet.com

The recommended dose of alpha-1 proteinase inhibitor is 60 mg/kg administered into the vein (intravenously) once weekly. Alpha-1 proteinase inhibitor should be administered at a rate of up to 0.08 milliliters for each kilogram per minute. On average, each infusion takes about 15 minutes.

Source: http://www.medicinenet.com

Alpha-1 proteinase inhibitor has not been adequately evaluated in pregnant women. Due to the lack of conclusive safety data, alpha-1 proteinase inhibitor should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. Alpha-1 proteinase inhibitor is classified as FDA pregnancy risk category C.

Source: http://www.medicinenet.com

It is not known if alpha-1 proteinase inhibitor is excreted in breast milk. Because many drugs enter human milk and can potentially cause harm to the nursing infant, alpha-1 proteinase inhibitor should be used cautiously in nursing mothers. REFERENCE: FDA Prescribing Information

Source: http://www.medicinenet.com

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