Drug: acarbose

The most common side effects of acarbose are:
  • abdominal pain,
  • diarrhea and
  • flatulence (gas).
There is a rare possibility that these gastrointestinal side effects may become severe and progress to paralytic ileus. Other possible but rare side effects include
  • an increase in liver enzymes, and
  • decreases in hematocrit, calcium or vitamin B6 levels.
  • Liver failure,
  • severe skin reactions, and
  • pneumatosis cystoides intestinalis infection.

Source: http://www.medicinenet.com

Yes

Source: http://www.medicinenet.com

Tablets: 25, 50 and 100 mg.

Source: http://www.medicinenet.com

Acarbose should be stored at room temperature, 15 C - 30 C(59 F -86 F) in a tight container.

Source: http://www.medicinenet.com

The recommended initial acarbose dose is 25 mg three times daily. The dose is then increased every four to eight weeks based on response and tolerance. The maximum dose is 50 mg three times daily for patients weighing 60 kg or less and 100 mg three times daily for those weighing more than 60 kg. Acarbose should be taken at the first bite of each meal. Smaller doses may be adequate for patients with severe kidney dysfunction or liver disease. Acarbose is not recommended if a patient has cirrhosis. Acarbose therapy is not advised in the presence of certain medical conditions such as inflammatory bowel disease or intestinal obstruction and chronic intestinal diseases that interfere with digestion or absorption such as Crohn's disease. Acarbose doses should be adjusted based upon blood glucose levels taken one hour after a meal and blood HbA1c levels taken about three months after starting or changing the dose. (HbA1c is a chemical in the blood that is a good indicator of blood glucose control.)

Source: http://www.medicinenet.com

There are no studies of acarbose treatment during pregnancy in humans. Insulin therapy is recommended in pregnancy.

Source: http://www.medicinenet.com

Acarbose is excreted in the milk of lactating animals, but no human studies have been conducted. Acarbose use is not recommended for women who are breastfeeding. Medically reviewed by Eni Williams, PharmD REFERENCE: FDA Prescribing Information

Source: http://www.medicinenet.com

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