Dosing is based on patient's ideal body weight. In adults a loading dose of 5.7 mg/kg administered intravenously over 30 minutes followed by a continuous maintenance infusion of 0.5 mg/kg/hr for non-smokers 60 years or younger and 0.38 mg/kg/hour for those 60 years and older.
Theophylline is excreted into breast milk and may cause irritability or other signs of mild toxicity in nursing infants. Therefore, it should not be used in nursing mothers or use with extreme caution under medical supervision.
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