Common side effects from ketorolac include:
- ringing in the ears,
- abdominal pain,
- heartburn, and
- fluid retention.
NSAIDs reduce the ability of blood to clot and therefore increase bleeding after an injury. Ketorolac may cause ulcers and bleeding in the stomach and intestines, particularly with use for more than five days. Sometimes, stomach ulceration and intestinal bleeding can occur without any abdominal pain. Sometimes, the only signs or symptoms of bleeding may be:
- black tarry stools,
- weakness, and
- dizziness upon standing (orthostatic hypotension).
NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously. Liver failure has also been associated with ketorolac.