If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them. Before you start using this medication for self-treatment, consult your doctor or pharmacist if you are also using any prescription and nonprescription medications. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: ketorolac, mifepristone.If you are currently using any of these medications, tell your doctor or pharmacist before starting aspirin.Before using this product, consult your doctor if you have recently received certain live vaccines (such as varicella vaccine, live flu vaccine).Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: acetazolamide, other "blood thinners" (such as warfarin, heparin), corticosteroids (such as prednisone), methotrexate, pemetrexed, valproic acid, herbal medications such as ginkgo biloba.Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers known as NSAIDs (non-steroidal anti-inflammatory drugs such as ibuprofen, naproxen). To prevent an overdose of aspirin, read the labels carefully before taking other pain relievers or cold products to make sure they do not contain aspirin. Ask your pharmacist about using these products safely.Daily use of NSAIDs (such as ibuprofen) may decrease aspirin's ability to prevent heart attack/stroke. If you are using low-dose aspirin for prevention of heart attack/stroke, consult your doctor or pharmacist for more details and to discuss other possible treatments (such as acetaminophen) for your pain/fever.This medication may interfere with certain laboratory tests (including certain urine sugar tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using this medication.This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.