Drug: avanafil

The most common side effects of avanafil are:
  • facial flushing (reddening),
  • headaches,
  • back pain,
  • nasal congestion,
  • dizziness, and
  • upper respiratory tract infections.
  • diarrhea,
  • nausea, and
  • flu-like symptoms
Avanafil also may cause low blood pressure, blurred vision and changes in color vision, and abnormal ejaculation. Avanafil may cause prolonged erections or priapism (painful erections lasting more than 6 hours). Patients should seek immediate medical help if they experience an erection lasting more than 4 hours. Use of avanafil, especially in patients with pre-existing heart disease, may cause
  • chest pain,
  • heart attacks,
  • death,
  • strokes,
  • palpitations, and
  • increased heart rate.
Rare cases of sudden loss of hearing have been reported with phosphodiesterase inhibitors such as avanafil, sometimes associated with ringing in the ears and dizziness. If changes in hearing occur, patients should stop their avanafil and seek immediate medical attention. Phosphodiesterase-5 inhibitors have been associated rarely with non-arteritic anterior ischemic optic neuropathy (NAION), a condition which causes decreased vision and may lead to blindness.

Source: http://www.medicinenet.com

Yes.

Source: http://www.medicinenet.com

Tablets: 50, 100 and 200 mg.

Source: http://www.medicinenet.com

Avanafil should be stored at room temperature between 20 C and 25 C (68 F and 77 F).

Source: http://www.medicinenet.com

For most individuals, the recommended starting dose of avanafil is 100 mg per day taken about 30 minutes before sexual activity. Depending on the adequacy of the response or side effects, the dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking medications that moderately increase the blood levels of avanafil should not exceed a total dose of 50 mg in 24 hours (See drug interactions).

Source: http://www.medicinenet.com

The breakdown and elimination of avanafil from the body may be decreased by several drugs, leading to increased blood levels of avanafil and possible toxicity. Ketoconazole (Nizoral), itraconazole (Sporanox), indinavir (Crixivan) and ritonavir (Norvir), atazanavir (Reyataz), clarithromycin (Biaxin), nelfinavir (Viracept), saquinavir (Invirase), telithromycin (Ketek) profoundly increase blood levels of avanafil and should not be combined with avanafil. The dose of avanafil should not exceed 50 mg daily when combined with erythromycin, amprenavir (Agenerase), aprepitant (Emend), diltiazem (Cardizem), fluconazole (Diflucan), fosamprenavir (Lexiva), and verapamil (Calan) because these drug moderately increase blood levels of avanafil.

Source: http://www.medicinenet.com

Avanafil is not approved for use in women.

Source: http://www.medicinenet.com

Avanafil is not approved for women and has not been evaluated in women who are breastfeeding. Medically reviewed by Eni Williams, PharmDREFERENCE: FDA Prescribing Information

Source: http://www.medicinenet.com

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