Drug: rabeprazole

Rabeprazole like other PPIs has few side effects. The most common side effects are diarrhea, nausea, vomiting, constipation, rash, and headaches. Dizziness, nervousness, abnormal heartbeat, muscle pain, weakness, leg cramps, and water retention rarely occur. High doses and long-term use (1 year or longer) may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine. Therefore, it is important to use the lowest doses and shortest duration of treatment necessary for the condition being treated. Low magnesium levels, leading to seizures, abnormal heart beats, and tetany (overactive reflexes) has been reported during long-term treatment. Reference: FDA Prescribing Information
Last Editorial Review: 1/4/2012

Source: http://www.medicinenet.com

Yes.

Source: http://www.medicinenet.com

Tablets (Delayed release): 20 mg

Source: http://www.medicinenet.com

Rabeprazole should be stored at room temperature, 15-30 C (59-86 F) and should be kept away from moisture.

Source: http://www.medicinenet.com

Tablets should be swallowed whole and should not be crushed, split or chewed. Rabeprazole can be taken with or without meals since food has little effect on its absorption.
  • For healing ulcerating GERD, the recommended dose for adults is 20 mg daily for 4-8 weeks. If healing does not occur after 8 weeks, another 8 week course may be considered. The recommended maintenance dose is 20 mg daily.
  • Heartburn due to GERD is treated with 20 mg daily for 4 weeks and an additional 4 weeks if symptoms do not resolve.
  • Ulcers are treated with 20 mg daily for 4 weeks.
  • For the management of Zollinger-Ellison Syndrome, the starting dose for adults is 60 mg daily, and the dose is adjusted based on improvement in symptoms, healing of ulcers, or the effectiveness of acid suppression. Doses of 100 mg per day and 60 mg twice daily have been used in some patients with Zollinger-Ellison Syndrome.
  • The regimen for eradication of Helicobacter pylori is rabeprazole 20 mg, clarithromycin 500 mg, amoxicillin 1000 mg all given twice daily (morning and evening) for 7 days.

Source: http://www.medicinenet.com

Use in pregnant women has not been adequately evaluated.

Source: http://www.medicinenet.com

Rabeprazole has not been studied in nursing women.

Source: http://www.medicinenet.com

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