Tell your doctor all the medications you're taking.
This also includes prescription and over-the-counter medications, vitamins and other dietary supplements (nutritional shakes, protein powders, etc.), herbal remedies and any illegal and recreational drugs.
Do not take isotretinoin if you are taking tetracycline antibiotics, such as doxycycline (Vibramycin) or demeclocycline (Declomycin, Declostatin, Ledermycin) or vitamin A.
Avoid taking isotretinoin if you're taking:
Talk to your doctor about the risks and benefits of taking isotretinoin if you're using:
You should avoid or limit drinking while taking isotretinoin.
The liver breaks down isotretinoin several different ways, one of them being the same as grapefruit juice.
Avoid grapefruit and the juice while you're taking isotretinoin.