Clinical Trial: Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional




Official Title: Phase 1 Safety Run-in and Phase 2 Randomized Clinical Trial of Anetumab Ravtansine and Pembrolizumab Compared to Pembrolizumab for Mesothelin-Positive Malignant Pleural Mesothelioma

Brief Summary: This randomized phase I/II trial studies the side effects and how well pembrolizumab with or without anetumab ravtansine work in treating patients with mesothelin-positive pleural mesothelioma. Monoclonal antibodies, such as anetumab ravtansine and pembrolizumab, may interfere with the ability of tumor cells to grow and spread.