Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)
Brief Summary:
Background:
Functional hypothalamic amenorrhea (functional HA) is a condition where a woman s period stops for a temporary time. This is due to improper function of the hypothalamus. This is the part of the brain that directs the whole reproductive system. Researchers want to learn more about functional HA. They also want to learn how diet, exercise, and other factors may change women s menstrual cycles.
Objective:
To better understand functional HA.
Eligibility:
Healthy women ages 18 28 years old who:
Have regular periods
Exercise no more than 4 hours a week
Had their first period at age 11 14
Design:
Participants will be prescreened over the phone.
Participants will be screened with:
Blood and urine tests
Medical history
Physical exam.
Participants will have 9 or 10 visits over about 3 menstrual cycles. These include:
Repeat of screening tests
Questionnaires
Exercise test
Resting energy expenditure test: Participants fast overnight before the test. They lie on their back under a