Clinical Trial: Intranasal Oxytocin in Hypothalamic Obesity

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Intranasal Oxytocin to Promote Weight Loss in Children and Adolescents With Brain Tumors and Hypothalamic Obesity Syndrome

Brief Summary: This research study will test if oxytocin, delivered by nasal spray, will promote weight loss in children and adolescents with Hypothalamic Obesity as compared to a placebo. The study is divided into two parts. During the first part, subjects will receive either oxytocin or placebo. In the second part, subjects will "cross-over" to receive the other treatment - either oxytocin or placebo. During study visits participants will do blood tests, physical exams, metabolic testing, a MRI scan, and some surveys and questionnaires.