Clinical Trial: Proof-of-concept Study of Birinapant in Combination With Platinum Based Chemotherapy in Subjects With High Grade Serous Carcinomas

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional




Official Title: A Phase II, Single Center, Proof-of-concept Study of Birinapant in Combination With Platinum Based Chemotherapy in Participants With Advanced Newly Diagnosed or Recurrent High Grade Serous Carcinomas

Brief Summary: This clinical trial is a Phase II, single center, open label, proof-of-concept study evaluating the efficacy of birinapant in combination with platinum based chemotherapy. This pilot study is aimed at determining the efficacy of carboplatin and birinapant co-therapy in treating patients with advanced newly diagnosed or recurrent high grade serous carcinomas. Only bio-assay positive patients will be enrolled