Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational
Official Title: Longitudinal Changes in the Oral and Gut Microbiome of Individuals With Alcohol Dependence
Brief Summary:
Background:
Many bacteria live in the gut. The gut is the tube that moves food from the mouth through the stomach to the intestines. Heavy alcohol use disturbs these bacteria. There is evidence that the bacteria in the gut may affect anxiety and depression. Researchers want to learn more about these bacteria in order to better treat diseases such as alcohol dependence.
Objective:
To identify the different bacteria that live in the mouth and gut. Also, to learn if these bacteria change as a person goes through alcohol detoxification.
Eligibility:
People ages 18 and older who:
Design:
Participants will have physical exams.
Participants will answer questions about:
Participants will keep a regular record of their diet.
Participants will have breath alcohol analysis 4 times per day.
Participants will provide stool and oral specimens at most once a day for the fir