Clinical Trial: tDCS and Its Therapeutic Effects in CK Fever

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Transcranial Direct Current Stimulation (tDCS) and Its Therapeutic Effects in Chikungunya Fever

Brief Summary:

One of the major challenges faced by researchers working in the field of rehabilitation science is the ability to provide integrative approaches to the use of clinical practice. In this context it becomes increasingly necessary to construct investigative approaches, so that they can reach clinical practice in a shorter period of time,since the large volume of information produced globally does not impact in the short or medium term on new therapeutic recommendations. Among the various chronic painful entities, there is chikungunya fever as a highlight for having a rich clinical chronology in relation to pain. Its therapy is used done by drugs in almost all national and international consensuses, therefore therapy against pain in chikungunya fever is limited during the rehabilitation process. It is very important that the science of rehabilitation enhances methods of noninvasive brain modulation that enable, through the excitation or inhibition of specific cortical areas to produce pain inhibiting effects, providing a simple and low cost treatment to the clinical routine.Technological advances and non-invasive techniques to modulate brain function have been developed, for instance, Transcranial Direct Current Stimulation (tDCS).

The objective of the present project is to present the tDCS as a new modality of physical rehabilitation for the patient with chronic pain resulting from chikungunya fever. The purpose of the study is to present physical, behavioral and social results of the application of tDCS in chikungunya fever, suggesting an improvement in the quality of life and functional status of the individual.


Detailed Summary:
Sponsor: Universidade Federal do Rio Grande do Norte




Current Primary Outcome:

  • Change from baseline Pain at 3 weeks [ Time Frame: Every day during 3 weeks (before treatment, during treatment and one week after treatment). ]
    Diary of pain
  • Change from baseline Pain at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Visual analogue scale.
  • Change from baseline Pain at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Diagnosing Neuropathic Pain - DN4 Questionnaire
  • Change from baseline Pain at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    McGill Pain Questionnaire short brazilian version (Br- MPQ)
  • Change from baseline Pain at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Brief Pain Inventory (Short Form).


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Change from baseline Quality of Life at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Short Form 36 Health Survey (SF-36).
  • Change from baseline Flexibility at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Sit and Reach Flexibility Test.
  • Change from baseline Flexibility at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Back Scratch Test.
  • Change from baseline Strength at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    The 30-Second Chair Stand Test.
  • Change from baseline Strength at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Elbow flexion strength test
  • Change from baseline Strength at 3 weeks [ Time Frame: baseline (one week before starting stimulation), one week after baseline (after first stimulation), eleven days after baseline (after last stimulation) and 3 weeks after baseline. ]
    Manual Muscle Testing (Hand Dynamometer)


Original Secondary Outcome: Same as current

Information By: Universidade Federal do Rio Grande do Norte




Dates:
Date Received: December 5, 2016
Date Started: December 12, 2016
Date Completion:
Last Updated: April 17, 2017
Last Verified: April 2017