Clinical Trial: Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Effects of Carvedilol on the Cardiovascular and Subjective Response to MDMA (3,4-Methylenedioxymethamphetamine, "Ecstasy")

Brief Summary: The purpose of this study is to determinate the effect of a pre-treatment with carvedilol, a alpha- and beta-adrenergic receptor blocker, on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The investigators hypothesize that carvedilol will attenuate the cardiovascular and subjective response to MDMA.