Clinical Trial: Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing Based on B-cell Reconstitution vs a Serologic ANCA Flare

Brief Summary: The purpose of this study is to determine the best management strategy to maintain remission in patients with ANCA vasculitis who have been treated with rituximab induced B cell depletion for at least two years. This study will compare intermittent B Cell depletion upon B cell return or intermittent B cell depletion upon serologic relapse.