Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy
Brief Summary: The study was a double-blind randomized controlled trial, carried out at the Department of Anaesthesia, Aga Khan University Hospital. Sample size was calculated to be 86 with 80% power at 5% significance level assuming a 30% difference in the mean narcotic consumption in the test group using NCSS~Pass (version, 11.04)(Reference for calculation). Patients were divided into two groups of 43 each, one received saline and the other received 0.5mg/kg ketamine before wound closure. Randomization was done with the help of sealed envelope method. All patients were observed in the recovery room for one hour to see the magnitude of post-operative pain using Visual Analogue Scale. The amount of narcotic consumption was noted. Data were analyzed using SPSS version 19.