Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: The NEUROlogically-impaired Extubation Timing Trial
Brief Summary: This randomized controlled trial will enrol patients with acute severe brain injury who pass a spontaneous breathing trial but have decreased level of consciousness. It will directly compare (1) prompt extubation vs. (2) prompt tracheostomy vs. (3) usual care, with extubation or tracheostomy timed according to physicians' discretion. The primary outcome will be ICU free days (days spent alive and outside an ICU).