Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational
Official Title: Effect of Deep Brain Stimulation in the Globus Pallidus Internus on Quality of Life in Young Patients With Dyston-dyskinetic Cerebral Palsy
Brief Summary:
There are limited therapeutical options for patients with secondary dystonia due to cerebral palsy. Pharmacotherapy is often without effect, or side effects are severe. Meanwhile deep brain stimulation (DBS) has proven to be a safe and effective therapy for patients with parkinson´s disease or primary / idiopathic dystonia. Experiences with DBS in patients with dyskinetic cerebral palsy are limited with heterogeneous data.
With STIM-CP we investigate the effect of DBS on quality of life in young patients with a dyskinetic movement disorder (dyskinetic cerebral palsy) due to perinatal hypoxic brain injury. Additionally, the effect of DBS on motor development, speech, memory, attention, cognition and pain perception will be assessed. In total, 20 patients aged 7-18 years diagnosed with dyskinetic cerebral palsy, who will receive DBS, should be included. 11 German DBS-centres will participate in the trial.
We assume that DBS reduces the severity of dystonia and improves the quality of life in these patients.