Study Status: NOT_YET_RECRUITING
Recruit Status: NOT_YET_RECRUITING
Study Type: INTERVENTIONAL
Official Title: An Open-label Phase 1 Study to Evaluate the Safety of SGN-35T in Adults With Advanced Malignancies
Brief Summary:
This clinical trial is studying lymphoma.
Lymphoma is a cancer that starts in the blood cells that fight infections.
There are several types of lymphoma.
This study will enroll people who have lymphoma, such as classical Hodgkin lymphoma, peripheral T-cell lymphoma including systemic anaplastic large cell lymphoma, diffuse large B-cell lymphoma, or types of primary cutaneous lymphoma.
This clinical trial uses a drug called SGN-35T.
The study drug is in testing and has not been approved for sale.
This is the first time SGN-35T will be used in people.
The study drug will be given as an infusion through a vein.
This study will test the safety of SGN-35T in participants with lymphoma.
It will also study the side effects of this drug.
A side effect is anything a drug does to the body besides treating the disease.
This study will have three parts.
Parts A and B of the study will find out the best dose and dosing schedule for SGN-35T.
Part C will use the dose found in parts A and B to find out how safe SGN-35T is and if it works to treat select lymphomas.