Clinical Trial: Ascorbic Acid Treatment in CMT1A Trial (AATIC)

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Phase 2 Study of Ascorbic Acid Treatment in Charcot-Marie-Tooth Type 1A

Brief Summary: Charcot-Marie-Tooth type IA (CMT1A) is the most prevalent hereditary peripheral neuropathy. Demyelination of peripheral nerves is the hallmark of CMT1A. Ascorbic acid has been shown to have a favorable influence on myelination in in vitro studies and in a mouse model for CMT1A. We will study the efficacy and safety of ascorbic acid treatment in young patients with CMT1A.