Clinical Trial: Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Brief Summary: The leading risk factor for corneal transplant rejection is abnormal blood vessel growth of the host bed. Vascular endothelial growth factor (VEGF) is thought to be a mediator of this corneal neovascularization (NV), therefore we would like to test the safety and efficacy of local VEGF blockade in the promotion of graft survival in high risk corneal transplants.