Clinical Trial: Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional




Official Title: Pharmacodynamic Evaluation of the ANTICALCIURIC Effect of Hydrochlorothiazide in Dent's Disease

Brief Summary: Intrarenal calcifications (nephrocalcinosis) is present in Dent's disease and likely contribute to progression toward renal failure. In order to prevent this complication it is usually proposed to treat affected patients during childhood with high doses of thiazides.