Clinical Trial: Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional



Official Title: Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation

Brief Summary:

To examine whether application of lidocaine spray in cervical preparation for second trimester dilatation and evacuation alleviates pain and is superior to current protocol of preparation without analgesia and superior to placebo.

Methods A prospective randomized placebo controlled trial consisting of three groups

  1. Lidocaine spray group (group 1)
  2. Placebo group (saline spray) (group 2)

  3. No intervention group (as currently in our protocol) (group 3)

    • Women undergoing dilatation and Evacuation in the second trimester and are about to go cervical dilation with osmotic dilators(laminaria) will be invited to participate in the randomized placebo control trial comparing lidocaine spray, placebo (saline) or no application (as current protocol).
    • Informed consent will be obtained from each participant
    • After enrollment patient will be randomized into one of the three study arms by a computer program
    • The patient will be placed in the lithotomy position and the cervix will be exposed using a sterile bivalve speculum.

    • Pain will be assessed in 3 places using a visual analog pain scale 10(no pain) to 100 (worst possible pain).

      0 after removal 15

    • Group1 :after speculum insertion 4 puffs (40mg) of spray will be applied to the cervix and after a 2 minute wait laminaria will be inserted.
    • Clinical data will be col