Study Status: Not yet recruiting
Recruit Status: Unknown status
Study Type: Observational
Official Title: Taste Disorders in Middle Ear Disease and After Middle Ear Surgery
Brief Summary:
Objectives
To evaluate the impact of taste disturbance in different types of chronic middle ear diseases and after middle ear surgery.
Hypothesis
That patients with chronic otitis media and cholesteatoma has taste disturbance already before surgery due to the disease itself, of course depending on degree of the disease.
That patients with otosclerosis, has a normal nerve function before surgery.
That patients with normal taste before surgery are more likely to notices a taste disturbance.
That nerve in continuity after surgery, even if it is maltreated, gives less taste disturbance than a divided nerve.
Methods
A clinical study has been launched that measures taste function with two different methods for taste measurements, electrogustometry (EGM) and the filter paper disc method (FPD) before and after middle ear surgery in patients operated with middle ear surgery because of otosclerosis, chronic otitis media and cholesteatoma. The investigators plan to include 120 patients in this study.
A parallel study of the patients own experience of the symptom has also been launched were the patients answer a questionary and a quality of life document. The investigators plan to include 300 patients in this study.
A histological study where specimens of CTN from healthy ears and from ears with chronic disease will be investigated with electron microscopy has also started.