Clinical Trial: Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Pilot Study of the Effect of Trastuzumab and GM-CSF on Children With Recurrent Ependymoma

Brief Summary: This study plans to detect the presence of trastuzumab by mass spectroscopy in relapsed posterior fossa ependymoma (PFEPN) tumor specimen pre-treated with a single dose of intrathecal (IT) trastuzumab, as well as to evaluate toxicity of intrathecal trastuzumab in combination with subcutaneous (subQ) Granulocyte-macrophage colony-stimulating factor (GM-CSF) in children with relapsed PFEPN