Clinical Trial: ValGanciclovir Versus ValAcyclovir for Viral Prophylaxis in Kidney Transplantation

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional



Official Title: ValGanciclovir Versus ValAcyclovir for Viral Prophylaxis in Kidney Transplantation

Brief Summary:

Our study will compare all kidney transplant recipients receiving valganciclovir vs. valacyclovir for one year following kidney transplant and compare:

  1. the incidence, magnitude and duration of CMV and EBV viremia in the first year after transplant.
  2. the side effects of the anti-viral drugs requiring dose reduction or cessation

In addition, we will test renal tissue obtained from any biopsies post-transplant (surveillance or clinically indicated biopsies) by both polymerase chain reaction (PCR) and fluorescence in situ hybridization to assess for latent CMV and/or EBV.