Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL
Official Title: Phase One, Open Label, Assessment of a Dengue-4-Virus-Live Virus Human Challenge - (DENV-4-LVHC) Virus Strain in Healthy U.S. Adults
Brief Summary: The purpose of this research study is to test a weakened form of an experimental dengue virus challenge at different doses to test if participants develop symptoms or circulating virus in the blood (called viremia).
When volunteers are exposed to dengue on purpose, it is called a "challenge" or Dengue Human Infection Model (DHIM).
The research team is collecting information about the safety of the challenge and the best dose to use.
The information may help us to make a dengue challenge (a DHIM) that will test vaccines to protect people from dengue.