Clinical Trial: Steroid-Antiviral Treatment in Rehabilitation of Facial Palsy

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Antiviral Treatment in Facial Palsy. Randomized Control Trial

Brief Summary: The purpose of this study is to assess the efficacy of antiviral medicine (acyclovir) in complete recovery of facial Palsy. Fifty patients (Males and females) with acute Facial Palsy within the first 3 days of onset with age ranged from 15-60 years old. Each patient submitted to the following clinical evaluation using House and Brackmann6 facial function scoring system and Synnybrook grading system neurophysiological assessment of facial nerve and muscles before and after the end of treatment and then after the end of first and second month of treatment. EMG will be done for facial muscles of both sides beside measuring facial nerve excitability to determine the excitation threshold by recording the minimum electrical stimulus required to produce visible muscle contraction. A difference greater than 3.5 mA between the affected and unaffected side is considered to be significant in terms of poor prognosis. Nerve conduction study of facial nerves of both sides using concentric needle electrode. Trigeminal Blink reflex for both side of the face. Facial functional recovery was defined as "good" or "complete" using the same criteria used in the 2001 practice guideline. Using the House and Brackmann6 facial function scoring system, we considered an outcome of grade I or II a good recovery.