Clinical Trial: Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation Study

Study Status: COMPLETED
Recruit Status: COMPLETED
Study Type: INTERVENTIONAL




Official Title: Tofacitinib in the Treatment of Refractory Axial Spondyloarthritis Patients: A Dose Escalation Study

Brief Summary:

The goal of this clinical trial is to assess the efficacy of tofacitinib in refractory axial spodyloarthritis (ax-SpA) with dose escalation from 10mg to 15mg.
Patients will start on 10mg and then divided into 2 groups (10 and 15) at 3rd month according to major improvement criteria.

The main question[s] it aims to answer are:

  • Efficacy and safety of tofacitinib in different doses
  • If escalation of tofacitinib is justified if clinical criteria is not fulfilled at 10mg