Clinical Trial: ERAS for Gastric Cancer Patients After NACT

Study Status: COMPLETED
Recruit Status: COMPLETED
Study Type: OBSERVATIONAL




Official Title: Short- and Long-term Outcomes Following Perioperative ERAS Management in Patients Undergoing Minimally Invasive Radical Gastrectomy After Neoadjuvant Chemotherapy: A Single-center Retrospective Propen

Brief Summary:

Background: Gastric cancer patients receiving neoadjuvant chemotherapy (NACT) are more vulnerable to perioperative stress.
Enhanced recovery after surgery (ERAS) is widely used in surgical patients aiming at reducing stress responses.
However, whether this approach is safe and feasible for gastric cancer patients received minimally invasive radical gastrectomy after NACT remained determined.
So, the objective of this study is to investigate the effects of ERAS for this special group of gastric cancer patients.

Materials and Methods: The data of gastric cancer patients who underwent minimally invasive radical gastrectomy after NACT were collected in this retrospective cohort study.
Patients were divided into an ERAS group and a conventional group based on whether they received perioperative ERAS management.
Propensity score matching was conducted to eliminate bias.
Pre- and postoperative inflammatory and nutritional marker levels, postoperative complications, recovery indices and 3-year OS and RFS were observed.