Clinical Trial: Rehabilitative Trial for the Rescue of Neurophysiological Parameters in Progranulin Deficient Subjects

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Rehabilitative Trial for the Recovery of Neurophysiological Parameters in Progranulin Mutation Carriers Through the Use of Transcranial Direct Current Stimulation (tDCS)

Brief Summary: In this randomized, double-blind, sham-controlled study, the investigators will evaluate the effects of frontal and prefrontal anodal transcranial direct current stimulation (tDCS) on neurophysiological parameters of cortical connectivity, assessed by transcranial magnetic stimulation (TMS), in asymptomatic subjects at risk and symptomatic patients bearing a pathogenic Progranulin mutation.