Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Interventional
Official Title: Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations
Brief Summary: The study will investigate the ability of a new PET tracer, 18F-AV-1451, to detect depositions of a protein, called tau, in the brains of people with a mutation in the tau gene that causes deposition of the protein, and in people without the mutation. A single 18F-AV-1451 scan will be performed on control subjects without MAPT mutations, presymptomatic mutation carriers, and symptomatic mutation carriers.