Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Observational
Official Title: Association of Serum Fibroblast Growth Factor 21 (FGF-21) Levels With Resting Metabolic Rate (RMR), in Children and Adolescents With Hashimoto's Thyroiditis.
Brief Summary: Thyroid hormone (TH) and fibroblast growth factor 21 (FGF-21) are reported to share common metabolic pathways and underlying mechanisms in terms of energy balance, thus affecting both thermogenesis and resting metabolic rate (RMR). Although FGF-21 levels has been studied in children and adolescents regarding obesity, body composition and insulin resistance, data in children and adolescents diagnosed with Hashimoto's thyroiditis are lacking. Therefore, the purpose of this study is to measure the RMR in children and adolescents diagnosed with clinical hypothyroidism due to thyroiditis Hashimoto just before starting levothyroxine treatment and after six months achieving an euthyroid state, and to detect any association between serum FGF-21 levels and RMR.