Clinical Trial: Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Multi-Center Study Using Allogeneic Stem Cell Transplantation Following Reduced Intensity Chemotherapy in Patients With Hemoglobinopathies

Brief Summary: The purpose of this study is to determine if treatment with reduced-dose busulfex, fludarabine and alemtuzumab (CAMPATH) followed by sten cell infusion will allow for donor stem cells to grow in patients with hemoglobinopathies bone marrow and restore circulating blood counts. In addition the incidence and severity of side effects and of graft vs. host disease (GVHD) will be monitored.