Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Hemorrhoids and Metalloproteinases, Observational Study
Brief Summary:
An association between hemorrhoidal disease and matrix metalloproteinases (MMPs) has been described previously. MMPs regulate extracellular structural proteins and tissue remodeling. Neutrophil gelatinase-associated lipocalin (NGAL) is involved in the regulation of MMP activity. The aim of this work was to study the relationship between the levels of MMPs and NGAL and different stages hemorrhoids.
The study provides potentially important insights to the understanding of the natural history of Hemorrhoids and MMPs and NGAL regulation.