Clinical Trial: Effects of Isotretinoin on The Gonads and Hirsutism

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: The Effects of Oral Isotretinoin in Women With Acne and Polycystic Ovary Syndrome

Brief Summary:

The investigators consider that there are some rising concerns about the use of isotretinoin by women of reproductive age with depleted ovarian reserve, hence it is important to detect the effect of isotretinoin on ovarian reserve.

There has not been a well-designed study evaluating its effects on the human ovarian reserve, hormone levels and menstrual cycles in women with polycystic ovary syndrome (PCOS). For this reasons, this study was administered to determine whether there is an effect of isotretinoin on the gonads and hirsutism in women with acne and PCOS.