Clinical Trial: Study of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Previously Immunized With JE-CV

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Assessment of the Memory Immune Response, Safety of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Previously Immunized With a Single Dose of JE-CV and L

Brief Summary:

The aim of the study is to investigate the memory immune response and the yearly persistence of the immunity against Japanese Encephalitis (JE) after vaccination with a new Japanese Encephalitis Chimeric Virus (JE-CV) in participants previously vaccinated with JE-CV.

Objectives:

To describe JE immune status before, and after a JE-CV booster dose in subjects previously vaccinated with JE-CV
To describe the immune status before, and immune response following JE-CV vaccination in JE-naïve control subjects.
To describe the safety (in terms of solicited and unsolicited adverse events) of a single dose of JE-CV up to 6 months after the last vaccination.
To describe all related serious adverse events (SAEs) and related deaths from 6 months to 5 years after vaccination in JE-CV-primed subjects.