Clinical Trial: Modulation of Lactase Expression by a New PPARgamma Ligand in Duodenal Biopsies

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Modulation of Lactase Expression by a New Synthetic PPARgamma Ligand in Ex-vivo Cultures of Duodenal Biopsies

Brief Summary: This study is designed to assess the effect of a new PPARgamma modulator on the expression and activity of the lactase enzyme in human intestinal epithelial cells. Based on their previous experimental results, the investigators hypothesized that modulating intestinal PPARgamma activity is a new pharmacological mechanism allowing the control of lactase expression and activity in the gut