Clinical Trial: Amphotericin-B and Voriconazole for Pulmonary Blastomycosis

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Case Series of Continuously-infused Amphotericin-B and Follow-up Voriconazole Therapy for Severe Blastomycosis Pulmonary Infections

Brief Summary: All patients with pulmonary blastomycosis requiring mechanical ventilation will have their blood concentrations measured for the antifungal drugs, amphotericin-B and voriconazole; as well as an analysis of the susceptibility of their infecting species of blastomyces. This information will then be analyzed relative to their rate of clinical recovery from this serious fungal infection.