Clinical Trial: Prevalence and Intervention of Hypomagnesemia in Users of Proton-pump Inhibitors

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Inulin- a Potential Preventive Dietary Supplement Against PPI Induced Hypomagnesemia

Brief Summary:

Hypomagnesemia is a severe side effect of longterm use of all available proton-pump inhibitors (PPIH). It develops due to intestinal malabsorption of Mg2+.

This study investigates the application of dietary inulin fibers in users of proton-pump inhibitors with such a hypomagnesemia. To this end, repetitive short-term trials of 14 days of orally administered inulin, separated by a wash-out period of 14 days each were performed in cases of PPIH and controls. This study was not blinded or randomized.