Clinical Trial: Stopping Antihypertensive Treatment amOng Hypertensive Patients in Primary Care (STOP-Trial)

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional



Official Title: Arrêt du Traitement Antihypertenseur Chez Les Patients Hypertendus Suivis en Médecine Générale / Stopping Antihypertensive Treatment amOng Hypertensive Patients in Primary Care: Th

Brief Summary:

The STOP-Trial is a prospective multicenter nonrandomized open study on grade I hypertension, performed by General Practitioners.

The main purpose of the study is to determine the factors associated with the rate of patients remaining normotensive one year after stopping their antihypertensive monotherapy or low dose dual therapy:

  • white coat hypertension
  • primary diagnosis by home blood pressure measurements (HBPM) /ambulatory blood pressure measurements (ABPM) /clinical measure
  • initial blood pressure level
  • compliance
  • therapeutic class versus others
  • age
  • gender
  • weight variation
  • modification of lifestyle
  • concomitant treatments and associated substances

The primary endpoint will be the rate of normotensive patients at one year (i.e. HBPM values <135/85 mmHg).