Study Status: Withdrawn
Recruit Status: Withdrawn
Study Type: Interventional
Official Title: Novel Imaging Modalities to Characterize Angiogenesis in the Bone Marrow Microenvironment in Multiple Myeloma (MM) and Its Precursor Disease
Brief Summary:
Background:
- Multiple myeloma (MM) is a type of malignant blood cancer. It affects the plasma cells, which help produce antibodies and fight infection. MM is nearly always preceded by a pre-malignant state, monoclonal gammopathy of undetermined significance (MGUS) or smoldering multiple myeloma (SMM). Currently, it is not possible to predict when someone with MGUS or SMM will develop MM. Also, the disease changes in those early states are not well understood. Researchers want to look at imaging studies of people with MGUS, SMM, and MM. They will study whether the growth of blood vessels can be used to predict disease progression.
Objectives:
- To use imaging studies to evaluate disease progression in multiple myeloma.
Eligibility:
- Individuals at least 18 years of age who have MGUS, SMM, or newly diagnosed MM.
Design: