Clinical Trial: The Pharmacokinetics of Fentanyl in Intensive Care Patients

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional



Official Title: The Pharmacokinetics of Fentanyl in Intensive Care Patients

Brief Summary:

This study is part of a project intended to develop guidelines to optimise the dosing of fentanyl in intensive care patients.

This study will focus on determining:

  • Whether the pharmacokinetics of fentanyl change during the ICU stay.
  • To what extent / the degree of change in fentanyl pharmacokinetics in ICU patients.
  • Which factors (e.g. physiological variables) that cause such a change.
  • Based on simulations, determine context-sensitive half-times of fentanyl in ICU patients.