Clinical Trial: Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational



Official Title: Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Brief Summary:

Background:

Gastric cancers are cancers of the stomach. Hereditary ones are passed from parent to child. Researchers want to gather data about hereditary gastric cancers. They want to learn about changes these cause in the body and about the genes involved.

Objective:

-To gather data about hereditary gastric cancer.

Eligibility:

  • People at least 2 years old with personal or family history with a hereditary gastric cancer.
  • People at least 2 years old with gene changes that lead to such cancer or a lesion that may be hereditary.

Design:

  • Participants will be screened in a separate protocol.

  • Participants will have:

    • Physical exam
    • Medical history
    • Blood tests
    • Scans
    • Photos of skin lesions and other findings
    • Gynecology consultation for women
    • Cheek swab (some participants)
  • For some participants, their relatives will be asked to join the study.
  • Some participants will be asked to allow the study to get stored tissue samples for relatives who have died.
  • Some samples will be sent to outside labs. All person